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The Federation of Infection Societies meeting 2018 (FIS 2018) is the premier infection conference of the UK, welcoming delegates from all disciplines of laboratory, preventive and clinical medicine within the spheres of infectious diseases, microbiology, infection prevention and tropical/travel medicine. Here, the most important issues facing modern infection practice are discussed and debated. FIS 2018 brings together some of the best and most thoughtful minds from around in the world to inform and participate.